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SPRING 2020 BIOLOGY 350 ANIMAL PHYSIOLOGY

Check often Canvas and web page for updates

GO TO LAB BIO350 web page

The lecture part of CLASS for sections 1-4 meets on Tue and Thursday

Room 116 Biology

Lecture 9:30 -10:45 AM Tue & Thur

(sections 1-4)


OLD EXAMS (used in a summer course; MS Word 2003 format)

2006 summer Test 1, Test 2, Test 3, Test 4

2009 summer Test1, Test 2, Test 3, Test 4

On Canvas will be a master test bank for years of old exam questions

Back to teaching page

Spring 2020:

Biology Building

 

see this clip to get you thinking about course content:

https://www.youtube.com/watch?v=WVvKnq5XT-g

Instructor: But did you resubmit lab reports to earn back points?
Student: No, but I wanted to.

Instructor: Did you come by office hours to ask for help?
Student: No, but I was going to.

Instructor: Did you attend every lecture?
Student: I attended the important ones. Doesn't that count?

 

Lecture: Biological Sciences, Rm. 116, T and TH 9:30-10:45 AM
LABS: See Canvas for course ( Lab web pages from 2011 have some resources you might find of use)

The Bio 350 teaching lab is located in the JSB Building
Labs for sections 1-4:

Section 001 LAB M 3:00 pm - 5:50 pm-Jennifer (primary TA and grader), no secondary
Section 002 LAB T 12:00 pm - 2:50 pm-Bookie (primary TA and grader), Jennifer (secondary)
Section 003 LAB W 9:00 am - 11:50 am-Jennifer (primary TA and grader), no secondary
Section 004 LAB W 12:00 pm - 2:50 pm-Patrick Rivera (primary TA and grader), Julia (secondary)

Text book: It is listed in canvas. I strongly enourge you to have a text book to read sections related to the topics covered in lecture and lab.

Why comparative neurophysiology is of interest [ PDF ]

FREE NEUROPHYSIOLOGY TEXT BOOK ON LINE (use for a review of basic concepts)
http://nba.uth.tmc.edu/neuroscience/m/s1/index.htm

Free background information on neuron morphology, conducting electrical, ionic bases of resting & action potential, and Synapse structure

 


BIOLOGY 350- ANIMAL PHYSIOLOGY
Instructors:
Dr. Robin L. Cooper
RLCOOP1@email.uky.edu
Office: Morgan building-226
Tel: 257-5950
Office Hours: email for time
WWW Home page (go to)

Dr. Melody Danley
mlda227@uky.edu

Office: 153 C, NEW ACADEMIC SCI BUILDING

Office Hours: email for time

Teaching assistants for the course:

Oluwabukola Omotola

ukola.omotola@uky.edu


Dr. Jennifer Rodriguez-Rivera

Jennifer.Rodriguez-Rivera@uky.edu

_________________________________

Julia Howell

Julia.Howell@uky.edu

Patrick Rivera

patrick.rivera@uky.edu

 

 

 

 

Down load PDF files: Course outline PDF, MS word  
Jump to on this page:

Course schedule (see below) (go to)

Download PPT files (go to)

COURSE OUTLINE

Biology 350

BIO350: Lecture Schedule for Bio 350, Spring 2020, Sections 1-4

THIS SCHEDULE MAY CHANGE AS WE GO ALONG. So updates will be posted in Canvas as well as here on web page.

Lecture, Day, Topic Reading

1 1/16 How one learns. Homeostasis, Krogh principle Introduction to course and physiology. (Why comparative physiology-PDF) ( ms word file of looking up stuff)

Can't focus while studying.... turn off Facebook, texting and listen to this and read book.

Stress relaxation here and here.

2 1/21 Molecules, Energy and Biosynthesis Movie-----
about COPD and O2 therapy (checkout this blog) and here is an Article (PDF)

3 1/23 Membranes, Channels and Transport/ Physical basis of neuronal function

4 1/28 Physical basis of neuronal function
Cool YouTube/Ted talk



5 1/30 Physical basis of neuronal function

6 2/4 Communication along and between neurons
Chill out a bit with this here

7 2/6 Communication along and between neurons

8 2/11 Communication along and between neurons

9 2/13 Sensory Mechanisms. lecture quiz !!!!!!!!!!!!!!!!!!.
You can do it.... think of this mouse (here)

10 2/18 Sensory Mechanisms (Review day in class)

11 2/20 EXAM DAY in lecture

LABS WILL MEET THIS WEEK (No pre lab test) FOR SECTIONS 1-4 - fun lab activities- content will be tested on.

12 2/25 Sensory Mechanisms/ Organization of Nervous System

.....Muscle (Muscle man Youtube Muscle man EMG music )

13 2/27 Muscle & Behavior

14 3/3 Muscle & Behavior

15 3/5 Cardiovascular

In case you need to chillout and relax from stress go here

16 3/10 Cardiovascular.

17 3/12 Endocrine ...Hypothalamus-Pituitary. 2nd Quiz on line in Canvas ( 2nd part of the behavior content- ECHO360)  (1st part of Circulation- ECHO 360)

3/17-3/19 No class, Spring break

18 3/24 Thyroid, parathyroid, adrenal and pancreas ( 2nd part of circulation-ECHO360, short 3rd part of circulation-ECHO360)

19 3/26 Cont. Endocrine (ENDOCRINE-ECHO360; neat clinical aspects of Endocrine -Echo 360) Medical ppt

Links used : https://mymonthlycycles.com/menstrual_cycle.jsp

https://en.wikipedia.org/wiki/Development_of_the_reproductive_system

https://courses.washington.edu/conj/bess/differentiation/differentiation.htm


20 3/31 EXAM #2 (Tuesday) MOVED TO APRIL 9th due to UK being on a "on line"  system

To relax this weekend you need to play music and study these web sites      
https://en.wikipedia.org/wiki/Einthoven%27s_triangle
http://courses.kcumb.edu/physio/ecg%20primer/ecgaxis.htm

21 4/2 Respiration (ECHO 360 for respiration)

22 4/7 Respiration
A very cool YouTube clip sent by your last year classmate: It is 4 minutes long and definitely a good watch. https://www.youtube.com/watch?v=YDspP4BhlTw

23 4/9 Respiration EXAM #2 (Thursday)          

24 4/14 Respiration/ Ionic and Osmotic Balance (ECHO 360 for all of OSM and RENAL)
https://abg.ninja/abg

http://www.rnceus.com/abgs/abgmethod.html

Ion Normal blood concentration range (mmol.L?1)
Sodium 135-145
Calcium 2.1-2.8
Potassium ~3.5-5.0
Chloride 95-105
pH 7.35-7.45
pCO2 35-45
HCO3- 22 to 26 mEq/liter ( some other sources 21-28 mEq/L)

25 4/16 Ionic and Osmotic Balance

26 4/21 Digestion / Heat and adaptations (ECHO 360 for all of GI-digestion)

( gut brain connections) (current article on poop) (also drugs & the GUT)

27 4/23 Digestion / Heat and adaptations / Catch up ; QUIZ 3

28 4/28 Heat and adaptations (ECHO 360 for heat and adapations)

29. 4/30 Reproduction/thermal regulation;Catch up & Exam review

Chill out a bit with this here  & have a good break here

A litte more chill'n here

......Wednesday 5/6......10:30-12:30 AM ....FINAL EXAM. Cumulative with emphasis on last 3rd section of class

https://www.uky.edu/registrar/spring-2020-final-exam-schedule


BIO 350 Lab Schedule: See your Canvas page.

The outline presented above is a tentative plan for the semester. Specific topics and assignments are subject to change.

Principal Learning Objectives:
(Same learning objectives from http://courses.cit.cornell.edu/biog1440/)
1. To gain understanding of the principles of how animals work at the molecular, cellular, and systems levels. This understanding will come not by memorizing a large body of facts, but by developing mental models of the various physiological processes (e.g. transport processes, cell-cell signaling, metabolism, thermoregulation, circulation, respiration…) that underlie life.
2. To gain skill in thinking like a physiologist. This requires both asking and answering questions about physiology, and so involves observing phenomena, generating hypotheses about the underlying mechanisms, and devising tests of your hypotheses.
3. To appreciate the physiological similarities and differences between the physiologies of humans and other organisms, and so to understand how the study of physiology is thoroughly relevant to your own life and to the world around you.

Additional Lab Guidelines
An essential component of learning in physiology requires the use of live animals. It is impossible to demonstrate the full extent of possible responses through textbooks readings or lectures. As emerging professionals, it is expected that all students will demonstrate respect and maturity when working with these animals. If any disrespect or intentional cruelty is inflicted upon the animals, it may be reason to be expelled from the course with an "I" (incomplete), "W" (withdrawal), or automatic "E" (failing grade) depending the timing and degree of the offense.
No horse play, cutting up, playing around, etc. is allowed in the laboratory. There are many students coming and going in the lab throughout the day and materials are sometimes shuffled around. Squirting someone with a solution in a syringe or a bottle can be dangerous. You might "know" it is water but another person does not. A 3M KCl solution can easily be mistaken for water, and can be very harmful if squirted by accident in someone's eye.

Every student will have to have completed the on line safety test and bring to the lab on the 1st day of your section meeting time. It is an easy test and you can take it multiple times until you get a 100 %. Either save and email your TA, or print it out and bring it to the first lab of the semester. The TA will check you off for having completed the exercise. The website for the safety test is:

http://ehs.uky.edu/authenticate.php

Animal care:
Even though you will be using primarily invertebrate animals in these laboratories no torture of the animals is allowed. If any torturing occurs to the animals it is reason to be expelled from the course with an "I" (incomplete) or possible a "W" (withdrawal) depending the timing within the semester.
No horse play, cutting up, playing ball etc.. allowed in the laboratory period. Squirting someone with a solution in a syringe or a water bottle can be dangerous. You might know it is water but another person does not. 3M KCl can be very harmful if squirted by accident in someone's eye.
We will use a fixative in the lab. The fix solution is a Bouin's solution (Prepared with saturated picric acid, formaldehyde and acetic acid; Sigma-Aldrich Co.). Some people are very allergic to the vapors of formaldehyde. If you know you are allergic please inform the instructor (Dr. Cooper) as soon as possible so we can make alternative plans. The fix solution is to remain in the vented hood.


 


Suggested readings

................PDF 1-Evol. Med PDF or MS WORD

................PDF 2- Ice Fish PDF or MS WORD

Look at oxidative stress paper (PDF)

 

 

 

 

 

EXTRA Note:

To the issue about CHOLESTEROL and fluidity of biological membranes within normal temperatures. There maybe differences in the teaching on this point in Cell Biology and Animal Physiology so keep in mind which system, animal or bacteria, and the normal operating temperatures for the organisms.

In relation to Bio350 ANIMAL physiology and NOT bacterial cells the point is that cholesterol decreases fluidity in biological membranes of mammals.

Lets see the text by Lodish et al., (4th edition, 2000) Molecular Cell Biology

Page 165:

"Membrane cholesterol is another major determinate of bilayer fluidity....... The net effect of cholesterol on membrane fluidity varies, depending on the lipid composition. ...... At the high concentrations found in eukaryotic plasma membranes, cholesterol tends to make the membranes less fluid at growth temperatures near 37C."


DOWNLOAD Powerpoint files ( ppt files)

How we learn (ppt) & Lecture 1: PPT#1
Lecture 2: intro PPT#2
Lecture 3: intro membranes
Lecture 4: neuro PPT #3; PPT #4
Lecture 5: Sensory PPT #5
Lecture 6: Muscle PPT #6 
Extra ppt on some different muscle types--- neat ppt 
Lecture 7: behavior PPT#7
Lecture 8: endocrine
PPT#8

Clinical endocrine (ppt)

Lecture 9: circulation (PPT)

Lecture 10: Respriation (ppt)
Lecture 11: OSM and renal
(ppt)

Lecture GI- PPT

Lecture temp- PPT



Just some more on Muscle ppt

Clinical heart stuff (ppt) ionic current in pacing PDF

 

 

Neat Information:

Muscle cramp and K + : http://www.ncbi.nlm.nih.gov/pubmed/23182013 " CONCLUSIONS: The effect of banana ingestion on EAMCs is unknown; however, these data suggested bananas are unlikely to relieve EAMCs by increasing extracellular [K(+)] or [glucose](p). The increases in [K(+)](p) were marginal and within normal clinical values. The changes in [K(+)](p), plasma K(+) content, and [glucose](p) do not occur quickly enough to treat acute EAMCs, especially if they develop near the end of competition."

..............................http://www.ncbi.nlm.nih.gov/pubmed/22157068..... Horses and hyperK diets http://www.ncbi.nlm.nih.gov/pubmed/10213428

Evolutionary Physiology 1994 (PDF)

.............PDF 1-Evol. Med PDF or MS WORD

................PDF 2- Ice Fish PDF or MS WORD

About Myelin (PDF1) & (PDF2)

About folic acid (pdf)

Male Brain (pdf)

Drug MDMA (ectasy) (PDF)

neg pH (pdf)

Imprint genes (pdf)

Music & Brain (pdf)

Kiss & Run (pdf)

Neat PDF on nerve gas agents (PDF)

The leech model and glia cells (PDF)

Muscle Growth (PDF)

Skeletal muscle fatigue (PDF)

Skeletal muscle (link to actin and myosin ratios....here)

Heart. MEA in rats PDF

 

 

STUDENT ACTIVITIES IN BIOLOGY

1. TRI- BETA

UK Beta Beta Beta Biology Honors Society

OVERHEADS used in class:

 

 

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